You can disable some of the keys you don't plan to use on your keyboard using the Logitech SetPoint mouse and keyboard software.
NOTE: If you don't already have SetPoint installed, you can download it. See Knowledge Base article 360023189014 for instructions.
To disable a key:
Launch the Logitech SetPoint mouse and keyboard software.
Start > Programs > Logitech > Mouse and Keyboard > Mouse and Keyboard Settings
Click the My Keyboard tab at the top of the SetPoint Settings window.
Select your keyboard from the product drop-down menu at the top left.
Click the disabling icon on the left toolbar to display the Keyboard Inactive Keys screen.
Select the check box next to any key you want to disable.
NOTE: You can click the "?" icon for more information.
Click Apply to save your settings and then OK to close SetPoint.