Periodically, I wake my computer from sleep and my MX Master 3 mouse will work but lose its customized functionality from Logi Options + (scroll direction, shortcuts, etc.). When I open the application, I see that the mouse is considered "inactive" so none of my customizations work. The only fix I have found is to reboot my computer, which is very annoying. I have tried to force quit the app and stop its processes, then reopen the app, but that does not fix the issue either. I am running Logi Options+ 0.51.7474 on Mac OS Big Sur. I have also had this issue in the past using the original Logi Options app. I submitted this issue in the feedback section of the app as well but wanted to see if anyone had any advice on how to remedy this issue.
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