You can disable some of the keys you don't plan to use on your keyboard using the Logitech SetPoint mouse and keyboard software.
NOTE: If you don't already have SetPoint installed, you can download it. See answer 360023192954 for instructions.
To disable a key:
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Launch the Logitech SetPoint mouse and keyboard software.
Start > Programs > Logitech > Mouse and Keyboard > Mouse and Keyboard Settings
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Click the My All-in-One tab at the top of the SetPoint Settings window.
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Select your keyboard from the product drop-down menu at the top left.
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Click the disabling icon on the left toolbar to display the Keyboard Inactive Keys screen.
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Select the check box next to any keys you want to disable.
NOTE: You can click the “?” icon for descriptions of the settings.
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Click Apply to save your settings and then OK to exit SetPoint.
NOTE: Some settings shown above may be limited to certain devices.