You can disable some of the keys you don't plan to use on your keyboard using the Logitech SetPoint mouse and keyboard software.
NOTE: If you don't already have SetPoint installed, you can download it. See answer 360023192954 for instructions.
To disable a key:
Launch the Logitech SetPoint mouse and keyboard software.
Start > Programs > Logitech > Mouse and Keyboard > Mouse and Keyboard Settings
Click the My All-in-One tab at the top of the SetPoint Settings window.
Select your keyboard from the product drop-down menu at the top left.
Click the disabling icon on the left toolbar to display the Keyboard Inactive Keys screen.
Select the check box next to any keys you want to disable.
NOTE: You can click the “?” icon for descriptions of the settings.
Click Apply to save your settings and then OK to exit SetPoint.
NOTE: Some settings shown above may be limited to certain devices.